Louis van Gaal updated the media at his press conference and pre-match interview with MUTV on his squad and their season so far.
Van Gaal told MUTV: "Van Persie is maybe injured but it is a minor injury so we'll wait and see."
At his press conference, the United boss reaffirmed his stance regarding Radamel Falcao, saying the Colombian forward has to prove himself to get regular game time at the club after he was left out of the matchday squad during the 1-0 defeat to Southampton last weekend.
That defeat left United in fourth place, making a title challenge looking increasingly unlikely. Van Gaal has said the aim at the start of the season was finish in the Champions League places, which his side remain on course for.
He told the assembled media: "That is our goal and that I have always said, even in the beginning. We want to be champion, but then you have to win matches against Southampton and Aston Villa away. When you are not doing that you cannot be champion.
"Our goal from the beginning was that we start a process to be within the first four because we want to play in the Champions League, and that is still our goal.
"At this moment we have played 21 matches and we are in the area of the four. We have to fight for it because a lot of other teams are willing the same goal.
“There are more clubs who are fighting, they have the quality of the players so it shall be a battle. Of course I think we can do it, but that's football, we lost against Southampton and we were the better team. That's football.”
United will have to improve their away form if they are to be sure of Champions League qualification having only won twice on the road so far this season. This weekend they face a side that has taken all of their points at home this season.
Van Gaal said: “I think their players will do everything to beat Manchester United. Every player and every team wants to beat Manchester United. QPR have a playing style that is difficult for us, we have seen that already. They play a lot of long balls, they have strong strikers and we have to beat them in spite of that.”