At the halfway point these two sides are level pegging, though Southampton have a slight edge when it comes to goal difference. Both sides will be looking to step up their challenge for a top four place during the first game of 2015.
To be played on Thursday 1st January 2015 at 15:00. Venue: St. Mary's Stadium, Southampton
Odds: Southampton 2/1, Draw 12/5, Arsenal 8/5
Having finished 2014 in the top four when many had written them off, the job for Southampton now is to prove their credentials by staying there, and they've got the perfect opportunity when they take on Arsenal in their first game of 2015.
They showed their discipline and fight in the draw against Chelsea, and Arsenal are favourites to take fourth place off them between now and the end of the season.
The Saints will be without Morgan Schneiderlin who received two yellow cards against Chelsea, but can welcome back Ryan Bertrand who was ineligible at the weekend.
Arsenal may have to make a change up front with Danny Welbeck regarded as a major doubt as they look to climb into the top four. Olivier Giroud is suspended so it could open up the opportunity for Lukas Podolski to get a rare start for the Gunners.
They are on something of a run having won their last two games against Queens Park Rangers and West Ham United, with the latter proving to be a significant scalp in the race for the Champions League places.
“It's a big match because both teams are playing good football, not because of the place in the table.”
“I think we are some points short of what we could have achieved [this season]. It's time to catch those points back.”
Nathaniel Clyne ★★★ out ankle
Jake Hesketh ★★★ out knee
Jack Cork ★★★ out ankle
Sam Gallagher ★★★ out knee
Jay Rodriguez ★★★ out ACL knee
Danny Welbeck ★★ questionable thigh
Theo Walcott ★ probable knee
Serge Gnabry ★★★ out knee
Aaron Ramsey ★★ questionable hamstring
Mikel Arteta ★★★ out calf
Jack Wilshere ★★★ out ankle
Mesut Özil ★★★ out knee
Vassiriki Abou Diaby ★★★ out calf