The finest hour in Celtic’s illustrious history came during a meeting with Inter Milan, with Jock Stein’s Lisbon Lions becoming the first British side to taste European Cup success back in 1967.
Almost half a century on and the two sides are set to do continental battle once again.
There will be no illustrious prize at stake this time around, just a place in the last-16 of the Europa League.
Plenty of interest will be shown in the fixture from all sides, though, with Parkhead set to be rocking when Italian giants roll into Glasgow.
Inter, though, are being backed to prevail on this occasion by one of those to suffer Celtic pain 47 years ago, with club legend Tarcisio Burgnich of the opinion that Serie A power should shine through against Scottish foes.
He said in The Herald: "It's a good draw. The Celtic of today are not the Celtic of our times. They are not a team with top players.
"Scottish teams have a good spirit, but are struggling these days and are certainly not the best in European football. Teams from Scotland were very, very strong, but they don't have the same quality as they had back when I played.
"For the Final in Lisbon, I knew we would be in trouble because we were missing Luis Suarez, our midfielder, who was the key to our team. Celtic should have won by more goals. Our keeper Giuliano Sarti made save after spectacular save in the second half. We even joked with him to let them score just to relieve the pressure on us!
"I remember the Scots as being particularly aggressive and a good team. But it would be nice to beat Celtic now."
Celtic will play host to Inter on February 19, before heading to the San Siro a week later.
Establishing a lead on home soil could be crucial for Ronny Deila’s side, with it important that they make the most of what promises to be an electric atmosphere.
Playing catch-up in Italy would be a tough ask, but Inter are not the side they once were either and it may be that they are there for the taking as they struggle to juggle the demands of domestic and European competition.