Few teams have busier physiotherapists than Arsenal and Newcastle United at the moment.
The two teams' medical staff have been overworked because of injury problems with masses of their players on the treatment table.
They meet this weekend and a staggering 23 players are unavailable for selection through injury or suspension.
It means that both sides will be fielding makeshift line-ups and the winner of the tie will be the team which copes best with being unable to put out their full-strength side.
Here are the players rated as injured, suspended or doubtful for Saturday's fixture.
Arsenal: Mesut Ozil (injured), David Ospina (injured), Abou Diaby (injured), Mikel Arteta (injured), Jack Wilshere (injured), Theo Walcott (injured), Nacho Monreal (injured), Aaron Ramsey (injured), Laurent Koscielny (injured), Calum Chambers (suspended), Mathieu Flamini (doubtful), Tomas Rosicky (doubtful).
Newcastle United: Davide Santon (injured), Siem De Jong (injured), Gabriel Obertan (injured), Jonas Gutierrez, Ryan Taylor (injured), Tim Krul (injured), Rolando Aarons (injured), Rob Elliot (injured), Steven Taylor (suspended), Moussa Sissoko (suspended), Fabricio Coloccini (doubtful).
The mounting injury problems at both clubs mean that players have had to be utilised out of position and Alan Pardew's and Arsene Wenger's managerial capabilities have been tested to the max so far.
As it stands, Newcastle seem to coping better with the loss of their absentees than Arsenal are.
Although the Gunners are currently ahead of Pardew's men it is only on goal difference and there can be no question they are playing below the sum of their parts.
Arsenal strengthened heavily in the summer and still have a number of talented individuals in their ranks despite the lengthy list of absentees.
Newcastle, on the other hand, seem to have found strength in adversity. After failing to win any of their first seven matches they have climbed the table at a rapid rate and they will be determined to pick up another three points this weekend at the Emirates Stadium.