The Chilean has been in top form but is starting to feel the burn.
Of course Arsenal also have the advantage of not needing the win. Arsenal have already qualified for the nbext round of the Champions League with a game to spare, along with German side Borussia Dortmund.
However it is not yet known who will finish top of the group. Despite their struggles in the Bundesliga Dortmund have been excellent in Europe. They top the group, two points ahead of Arsenal.
The Gunners know that they finishing top of the group will be a massive boost to the team and should, in theory, reduce the quality of the team they face in the second round.
But Wenger has also been speaking of the need to give the players who have been playing on a regular basis a rest, in particular Alexis Sanchez.
He recently described the Chilean as in the red-zone and gave a very swift answer when asked by the press whether Alexis would be rested against the Turkish giants. Wenger simply stated when asked 'would Alexis be rested against Galatasaray?:
It means the like of Lukas Podolski, Joel Campbell and perhaps even Ainsley Maitland-Miles could get a game under their belts this week, especially with Olivier Giroud ineligible, Theo Walcott still suffering with a groin injury and Yaya Sanogo a maybe.
So while resting Alexis seems a sensible decision, it might cost Arsenal top spot in the group.