The former Premier League midfielder has been forced to call time on his playing career at the age of 33 due to injury.
The 33-year-old has been a free agent since leaving the Potters last season and officially announced his retirement on Twitter earlier today.
Etherington spent three years at Spurs after leaving Peterborough United, before playing for West Ham for a further six years.
The midfielder then joined Stoke in 2009, going on to spend five years at the Britannia Stadium. Etherington was keen to thank all those who supported him, as well as all the clubs he turned out for.
1/1 Due to an ongoing back problem, the day has come for me to retire from professional football. I have some amazing memories since the day— Matthew Etherington (@mattyethers) December 3, 2014
2/2 I made my debut at just 15yrs old. Thank you to all the great clubs I have played for and to the supporters. I have made some mistakes— Matthew Etherington (@mattyethers) December 3, 2014
3/3 along the way but it has made me who I am today. I look at the past with pride and to the future with optimism.— Matthew Etherington (@mattyethers) December 3, 2014
Pundit and former team-mate of the 33-year-old's, Danny Higginbotham, was quick to pay tribute to the former Stoke man on Twitter.
Etherington represented England at several youth levels up until the Under-21s, although he never earned a senior cap for the Three Lions. He was known for his pace and pinpoint deliveries from out wide. What next for the former Tottenham, West Ham and Stoke man?