Arsenal: Martinez, Chambers, Mertesacker, Koscielny, Monreal, Flamini, Ramsey, Cazorla, Oxlade-Chamberlain, Alexis, Welbeck
Subs: Macey, Gibbs, Bellerin, Rosicky, Podolski, Sanogo, Giroud
Southampton: Forster, Clyne, Fonte (c), Alderweireld, Bertrand, Wanyama, Cork, S. Davis, Tadić, Long, Pellè
Subs: K. Davis (GK), Yoshida, Gardos, Mané, Mayuka, Reed, Targett
Wenger has had several injury problems to contend with this season but he has solid options in all positions, which should allow Arsenal to name a strong side for the home game.
A win for the Gunners puts them to within two points of Manchester United, who currently hold the final Champions League place.
For Southampton the job is simple; make sure there is no repeat of the performance which saw Manchester City run out 3-0 winners in the game last weekend.
This is a big test for the Saints and their position at the end of the season will likely be determined by their performance in matches like this, against the sides they’re competing for European places against.