The Manchester United boss had good and bad news on the injury front after the win over Hull.
Even the most of ardent of Manchester United's foes must admit that the Premier League giants have had a torrid time with injuries this season.
And unfortunately for those associated to the club, it seems every passing game brings new problems.
During their 3-0 win over Hull at Old Trafford, fans will have been left especially concerned after record signing Angel di Maria and captain Wayne Rooney looked the latest to succumb to injury problems.
Even though Di Maria came off early on with a hamstring strain, it looked like he didn't catch the injury before it flared up enough to rule him out of the club's next fixture.
"He [Di Maria] did not come off as a precaution - he is out of Tuesday's game against Stoke," declared Van Gaal after the game. "It's too close.
"But we will have to wait and see how bad it is. We will know more tomorrow."
One ray of sunlight on the injury front is that the injury problem with captain Rooney may be a little more manageable.
The striker had been on the end of heavy challenges, including one from former Red Devil Robbie Brady, leaving him visibly uncomfortable as he hobbled around for a portion of the game, but Van Gaal was much more hopeful on his goalscorer's availability, with Rooney managing to finish the game.
"He has already told me he wants to play against Stoke," the Dutchman smiled. "But Rooney always says that."
Van Gaal added: "First he had a kick to his calf, I believe.
"After that he had a problem with his knee but I don't think that it is too much to worry about because he said that he should play."