How will the Gunners line up against Jurgen Klopp's side?
Some changes will be enforced, however, as Jack Wilshere's injury means the midfielder will miss out - and could be out for an extended period.
Wojciech Szczesny will also miss out, while David Ospina was already unavailable, meaning Damian Martinez should be in line for his second European appearance of the season.
Danny Welbeck, meanwhile, could also reportedly miss the Dortmund clash through injury and so could be replaced by Chuba Akpom.
Yaya Sanogo, of course, could stand in for Welbeck as Olivier Giroud is ineligible because he has not been registered for this season's Champions League campaign. But the 21-year-old has hardly impressed during his Emirates career and Arsenal boss Wenger could look to 19-year-old Akpom instead.
Predicted Arsenal XI v Dortmund
GK - Damian Martinez
LB - Kieran Gibbs
CB - Nacho Monreal
CB - Per Mertesacker
RB - Calum Chambers
CM - Mikel Arteta
CM - Aaron Ramsey
CM - Santi Cazorla
FW - Alex Oxlade-Chamberlain
ST - Chuba Akpom
FW - Alexis Sanchez