The academy pair are both yet to make their first-team debuts, but they are set to be named in the team tomorrow.
Winks and Ball have been in fine form for the development squad this season and Pochettino confirmed that he would reward the youngsters in his press conference today.
"Maybe they [Aaron Lennon, Vlad Chriches and Aaron Lennon] will be involved as well as one or two young players from the academy – Dominic Ball and Harry Winks," he said. "It’s important for them to be involved with the first team and it’s an opportunity to show their skill and to show the reality that we have a strong squad.”
It is a show of faith in Spurs's academy-system from Pochettino, which should please supporters of the club.
The Argentine manager proved that he was happy to trust youngsters during his time at Southampton and he has already commented on his desire to utilise the club's academy-system since being placed in charge.
One of his major successes so far has been Ryan Mason, who has shown great ability since stepping into the side.
Harry Kane and Danny Rose have also been regular features in the team and it seems that Winks and Ball could be the next youngsters to make the step-up.
Winks plays in central midfield, while Ball is a commanding centre-back and they would both be looking to impress in positions which have proved slightly problematic for the first-team if they did get on the pitch.
Spurs are looking comfortable in their Europea League group and should have no problems qualifying so it could be an ideal, unpressurised environment to help ease the prospects into life in the first-team.