Welbeck, seen as a dispensable option by Louis van Gaal, left the Old Trafford outfit for North London on the final day of the summer transfer window, ending a 15-year affiliation with the club.
Neither forward had the most exhilarating of games, although it's fair to say Danny Welbeck was far more involved for his side. The Englishman recorded 36 touches, compared to the mere 12 accumulated by Van Persie throughout his 74 minutes.
Welbeck will have been disappointed not to have scored against his former side. He proved far more of a threat than his ex-teammate in an attacking capacity, managing five attempts at goal, two of which were on target. Meanwhile, the Dutchman failed to manage a single shot.
In creative terms, the Arsenal man also emerged superior. Welbeck fashioned three key passes, while Van Persie created two scoring chances.
Van Persie clearly struggled to make his mark on the match, and this is highlighted by the statistical data. His passing accuracy will be a huge to concern to the Old Trafford faithful. Here, his ability to retain possession and link up with teammates certainly came under question.
The veteran forward attempted a stunningly low three passes for Louis van Gaal's men, while he was dispossessed on one occasion. Welbeck proved far more prolific in this department, having completed 80% of his 25 attempts to find a teammate.
Off the ball, Welbeck was seen contributing far more regularly. He weighed in with one tackle, one clearance and one blocked shot, while van Persie made two clearances.
Welbeck may have been shipped out of Old Trafford during the summer window, but it was the England international who most impressed in this tie. Van Persie has looked a shadow of his former self so far this term, with his poor form continuing against his former club.