Keane, who has scored 65 goals in 136 games for his country, has also been released from playing in the upcoming friendly with the US on Tuesday.
Various media outlets have speculated whether the move by Ireland boss Martin O'Neill, going with Shane Long and Jon Walters supporting him, could signify the beginning of the end for the country's record goalscorer.
However, both the player himself and O'Neill have rubbished such claims, with Keane particularly forthright in his understanding of why he started the game with Scotland on the bench.
"If the manager wants to play with one up front, I'm not Niall Quinn or I'm not Shane Long - they are better at that than I am,” Keane said.
“If you play two up front and you want to score goals, that's my game.
"Listen, I'd prefer to speak about the team rather than an individual, making a big deal out of someone else starting the game.
"The manager made a decision and you have to respect that. Playing one up front doesn't suit me, I think that's fairly obvious. I'm 5' 10", so it's not my game."
The 34-year-old will now concentrate on LA Galaxy's Western Conference Championship matches with Seattle Sounders.