Aston Villa may have suffered another injury blow on Wednesday night, with captain Ron Vlaar limping off in only the 24th-minute of the Netherlands' friendly against Mexico in Amsterdam.
Details are still to emerge on the severity of the injury, but it's believed that the 29-year-old has aggravated his troublesome calf for the second time this season.
Vlaar previously missed four league games this term after straining the same calf in the 1-0 home win over Hull City on August 31, with the Dutchman returning to action in the 3-0 defeat at Everton on October 18, going on to make it through the next three matches unscathed.
News of his injury comes just 24 hours after fellow Villa centre-back Philippe Senderos had to withdraw from international duty with Switzerland after also picking up a calf muscle issue, with the former Arsenal man returning to England for treatment.
With Nathan Baker already a doubt for the club's next league game against Southampton after twisting his knee in last weekend's 0-0 draw at West Ham United, Paul Lambert's side could be left incredibly short at the back.
Ciaran Clark and Jores Okore are now seemingly the only centre-halves left standing, while the latter is still to make a first-team appearance this season after rupturing his anterior cruciate ligament last season.