The Premier League side must table an offer too good to turn down if they are serious about prizing the Argentine away from Serie A and the San Siro.
Inter Milan have been clear in their attitude toward Tottenham and their reported interest in striker Mauro Icardi for some time: the 22-year-old is not for sale.
But as the season ticks on and the Nerazzurri continue to underperform on the pitch as well as off it, financially, would the Milan club be wise to sell their biggest asset?
The days of players being unavailable for transfer at any price are a thing of the past – Tottenham fans know all too well, having seen Gareth Bale depart the club two summers ago.
Even Inter have experienced this phenomenon in its earliest phase back in the summer of 2002 when the seemingly irreplaceable Ronaldo left for Real Madrid.
And while Tottenham may not be Los Blancos, the Nerazzurri would be wise to remember the old adage that Arsene Wenger sticks so stringently to – namely, that no player is bigger than the club.
More importantly, unless Inter fail to sell the likes of Icardi and reinvest in their mixed bag of a squad, they could find themselves even further off the pace both domestically and in Europe.
Currently 9th in Serie A, 10 points off leaders Juventus, and competing in the Europa League, Inter are a far cry from the side that won the Champions League under Jose Mourinho four years ago – a team that even then was build on creaking legs.
More concerning still are the financial figures floating around the club at present – losses of €103 million last year alone with owner Erick Thohir calling for change at the very heart of Italian football.
And while Inter are not the only Serie A club struggling financially at present, they do have a major asset in Icardi who could hold the key to forging a path out of their current predicament.
Tottenham have already had a €25 million bid for Icardi turned down, but if they return with a cash plus Roberto Soldado deal for the striker, Inter would be wise to take it.
Icardi may be a superior striker with a bright future ahead of him but the painful reality is that if he continues to impress, sooner or later another big club will come for him and Icardi will push for a move, because that’s what players do.
Soldado may have endured a nightmare in the Premier League but a Serie A switch could see the Spaniard return to the kind of form that made him a goalscoring sensation in Spain with a so-so Valencia side.
Get him scoring again and Inter have a striker capable of leading the line for the next three seasons as a minimum as well as €25 million to spend where required.
On a more cynical note still, Icardi’s current form could represent a peak and the perfect time for the club to cash-in on an asset before any potential dip in form.
The Argentine may have previously spoken of his desire to form a bond with the fans but how will he feel if Inter fail to qualify for Europe next season and he fails to break into the Albiceleste national side – supporter appreciation will be his last concern.
More importantly, with the forward previously hitting out at the fans for booing the team, poor results could bring a change of perspective on his future.
From Tottenham's perspective, meanwhile, Icardi is the kind of striker who could help Spurs move from Europa League also-rans to Champions League contenders, in a Premier League that looks increasingly like Manchester City v Chelsea for the title with the leftovers for the rest.
A top four finish is ripe for the taking and Spurs have almost all the ingredients to do just that – they just need a striker like Icardi to add the finishing touch.
For Tottenham and their Argentine target, it’s increasingly looking like a case of either thriving together or fading out alone.