The Manchester United legend poured cold water on any potential return to Old Trafford for Shawcross.
The England cap left United for the Britannia in 2008 as a promising youngster that was struggling to get game time under Sir Alex Ferguson.
With just two League Cup appearances under his name, Shawcross looked like he would be another youth that wasn't quite good enough for Old Trafford.
However, the giant centre back has gone on to be one of the most recent success stories of the United academy, despite having moved away from Manchester, notching up over 250 Premier League appearances at Stoke, most as captain, and earning England recognition.
That form has seen Shawcross linked with a return to his former club on more than one occasion, and the most recent news is that Louis van Gaal is happy to head to Stoke to solve his central defensive problems, especially considering United are rumoured to have included a £12 million buyback clause as part of the deal that originally saw him leave Old Trafford.
Whatever rumours there are in the press about the player, Hughes, who himself returned to Manchester United after leaving as a 23-year-old, was quick to rubbish them.
"I'm not sure where that originated from - I think somebody told me it might have come from America at some point," the former Wales boss said.
"There's been no contact and I don't expect there to be any, and we wouldn't encourage any contact anyway.
"Ryan is very settled here, he is the captain of the club and we have no intention of allowing him to leave.
"He's a big part of what we want to do in the future."
The fact Shawcross's contract is due to expire next summer may influence Stoke's position, as, if he hasn't signed a new deal come January, they may wish to cash in on the 27-year-old rather than risk losing him for nothing.