Both strikers were brought in by the Hammers over the summer and have made a positive initial impression.
Sakho believes that this is because they complement each-other well, with both having strengths and weaknesses in different areas of the game.
"I train with Enner just as I train with everyone else," he said to the club's official site. "We're trying to be in sync with one another."
"Enner is a much more technical player than I am, Me, I'm better suited to individual battles, to breaking the lines and getting defenders running back toward their own goal. Enner is more someone who likes to be in possession of the football. And so we complement one another."
"It's far too early to say what heights we can reach as a team. We know that the club targets are already set, but in relation to us as players in the here and now, it's to be among the top ten. If we can do better, then better still for us and for everyone. We've got a lot of quality, individual and collectively and so we've got to put it in to progress and to aim high."
Sakho has already scored five times in the Premier League, whilst Valencia has only hit the back of the net once, but they have been a major reason behind the success the club have had so far.
The pace of the pair is a threat to all defences across the league and it is helping to allow the Hammers more space on the ball.
Sam Allardyce has come under criticism for the style of play which he has imposed on West Ham since taking over, but this season the team seems transformed.
Playing at a high-tempo, with a precedence put on retaining possession, they have entertained and collected points at a rapid rate.
Already there is talk that they could reach the European places and a win over Burnley this weekend is likely to raise expectation even further.