Erik Lamela may be a doubt for Tottenham Hotspur's match against Manchester City on Saturday after his international commitments this week.
Lamela is in the Argentina squad who are currently in Hong Kong after playing in China on Saturday.
It means that he will have done a lot of travelling over the past week and the time difference is sure to be hard to get used to when he does return to England.
Spurs are the early kick-off on Saturday, meaning he will have fewer than 48 hours to adapt to being back in England before traveling to Manchester and only another 24 before he is forced to play a match.
It is a highly demanding schedule that Mauricio Pochettino may have to manage carefully if he is to keep Lamela's confidence high.
It is likely that he could be forced to sit on the bench against Manchester City at the weekend, with fatigue likely to play a part if he does start.
Lamela has made giants strides forwards this season and the potential loss of one of the biggest attacking threats against the current Premier League champions is sure to be a blow.
There can be few expectations on him if he does start, given his gruelling week, and it may mean that a backseat role will favour him in this match.
If he does get a well-deserved rest then it is likely that Harry Kane will come in and it could be a big opportunity for the English youngster.
Kane has had to make do with a number of substitute appearances this campaign, but he may be able to force his way back into the starting line-up if he can make an impact against City.
Manuel Pellegrini's side look more vulnerable than they did during the last season, but they will still be huge test for Spurs to beat and any points that Tottenham return with from the Etihad will be a major bonus.