Mesut Ozil has been ruled out for 10-12 weeks with a knee injury picked up on international duty this week.
The Arsenal attacking midfielder went for scans on the complaint today and Germany announced the news of their official Twitter.
BREAKING: @MesutOzil1088 out for 10-12 weeks with partial lateral collateral ligament tear in left knee. More to follow... Get well soon!— Germany (@DFB_Team_EN) October 8, 2014
It is another injury complaint for Arsene Wenger to have to deal with just at a time when a number of his first-team stars appeared to be coming back to first-team contention.
The likes of Theo Walcott and Serge Gnabry were both heading closer to a comeback and the thought was that Ozil may have thrived with the added pace in the team.
The creative midfielder has struggled for form recently and has come under scrutiny for his performances, but there were hopes that he would improve.
Instead, he is now likely to be out for most of the remainder of the year and that serves as a major blow for Wenger's side.
It puts greater pressure on their attacking signings, Danny Welbeck and Alexis Sanchez to perform, whilst the rest of the squad will have to step up to add creativity in Ozil's absence.
Arsenal's first fixture after the international break comes against Hull City and it will be intriguing to see how much of a threat the pose without the main creative influence on their side.