United were hit with a blow yesterday when news emerged that new £30 million Spanish midfielder Ander Herrera is set for a spell out with a fractured rib.
The former Athletic Bilbao man will be heavily missed as he has been one of the positives of United's otherwise poor start to the new season.
Dutch manager Louis Van Gaal must now decide who the best person is to fill the energy and dynamism that Herrera brings to the United midfield.
With Michael Carrick still out injured, Van Gaal's options are limited to Darren Fletcher, Marouane Fellaini and Anderson. The first two are not really mobile enough to make up for the loss of Herrera in that right-sided central midfield spot, those pair are most suited to a holding position.
Anderson has had more than enough chances at United and it's unlikely even with injuries that he will get that near the first-11 again this season.
One player who Van Gaal should take a real look at is Belgian-born Brazilian Andreas Pereira.
The 18-year-old plays in a similar mould to the injured Herrera; he's energetic, good on the ball, not afraid to go forward and surprisingly strong for someone of his slender build.
Pereira has been one of the standout players in the United reserves and youth team for a number of seasons now, and was rewarded with his United debut in the dismal 4-0 drubbing to MK Dons, coming on as a second half substitute.
He is in the last year of his contract at United and the club are yet to begin discussions on a new deal. It's likely that along with a new contract, Pereira will want some assurances over his position in the side. United want to avoid another Paul Pogba situation at all costs.
First and foremost the youngster will have to prove himself in training before he reaches the first team again, but the United manager has already given Premier League debuts to five young players already this season. So it might not be too farfetched to think that Pereira could be next in line.