Manchester United take on West Ham United this weekend. However Louis van Gaal goes into the game with serious problems in defence.
Tyler Blackett is suspended, while Jonny Evans, Phil Jones and Chris Smalling are all out injured. Manchester United failed to bring in central-defender reinforcements in the summer and left-back by trade Marcos Rojo will be playing at the heart of United's defence alongside Tom Thorpe or Paddy McNair.
Last weekend their defensive frailties were clearly on show as they conceded five against Leicester City, losing a thrilling game 5-3 at the King Power Stadium.
But what silver lining can Louis van Gaal take from that game?
Well, with LvG needing to rely on players from the Manchester United academy, it was good to see a few former United graduates in action for Leicester City in that game.
Danny Drinkwater played a superb game in the heart of Leicester's midfield last Sunday. He was at United from the age of 16 but left in 2009, having never featured in a first team game for United.
Then there was right-back Ritchie De Laet. He struggled at times up against Radamel Falcao and Angel Di Maria defensively. But he had a great second half. De Laet was snapped up from Stoke City in 2009 at the age of 20. He spent three years at the club, playing six times, before joining Leicester City in 2012.
Add to that the second half arrival of Matty James, who was at the club from 2007 until 2012 and is the older brother of Reece James, and it was three former United youngsters, who never made the grade at Old Trafford, who helped embarrass their illustrious former employers.
Add to that the former trialist at United Jeffrey Schlupp coming into the game and their is reason to be positive. The young stars at United, even those who don't make it at the club, are often good enough to go on and forge themselves careers in the Premier League regardless.
So United fans should not worry too much about Thorpe and McNair this weekend if they can play to their full potential.