High-flying Southampton have now won five consecutive matches in all competitions, following Tuesday's Capital One Cup win at Arsenal, and they come into the game against QPR in full confidence.
Harry Redknapp's team have been highly inconsistent and their away form will be of great concern for supporters travelling to St Mary's this weekend.
The Dutchman can influence any game with his driving runs from deep and his long-range shooting is always a threat for opposing goalkeepers.
Southampton will expect to seal all three points in relatively comfortable fashion, but if Fer and his teammates can nullify their threat in midfield, it could be a close affair.
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Schneiderlin has played in every minute for the Saints so far this season and has already found the net three times.
Fer has created six more chances than the Southampton man, but the Frenchman has outperformed him in key defensive areas, while also completing more passes per game.
Schneiderlin is a key player for the Saints, and if he can control the tempo from midfield against QPR, Redknapp's side could be in for another drubbing away from home.
Fer will hope to prevent him from controlling the game, whilst also looking to create opportunities for those further up the pitch.
QPR will be desperate to leave with at least a point, but Southampton will be looking to make it four wins on the bounce in the Premier League.