Chelsea's assistant first-team coach Steve Holland has revealed that Ramires will not be available for selection when they take on Bolton Wanderers in the League Cup tomorrow night.
The Blues face the Championship side as heavy favourites to win the tie, but they will have to deal without Ramires if they are to win.
The Brazilian was substituted in the side's 1-1 draw with Manchester City at the weekend after picking up an injury and Holland has revealed that it will keep him out of Chelsea's match tomorrow night.
He said to the Chelsea's official site: "Ramires had a problem in his abductor muscle in the game which resulted in him being substituted in the second half. It is a minor injury but it will keep him out of the game against Bolton and we will review him in the days following that."
Whether Ramires would have played in the tie, even if he was fit remains another question, though.
Jose Mourinho is expected to make a number of changes for the Capital One Cup clash, to rest some of his key players and Holland confirmed that the Portuguese manager would be looking to utilise some of the players in his squad who are yet to have a chance in the first-team this season.
"We have looked at the players following the game against Manchester City and it is an opportunity to rotate, we will do that for sure, but in terms of who is playing and who isn’t, that is unclear," he said.
"We have a small group of players who I am sure have been frustrated not to have played more and will possibly have the opportunity to show what they can do tomorrow."
The League Cup is not likely to be high up on Chelsea's list of priorities this season, but they will be looking to keep their momentum going.
Mourinho's men are unbeaten throughout the campaign so far and they will be determined to avoid an upset in the cup competition.
Although many of their first-team stars may not make an appearance, there is a huge depth to Chelsea's squad and they should still have enough quality to come through.
Bolton have not made the best of starts to life in the Championship, but they will at least be able to play without pressure on Wednesday night.