The recent meetings between the two sides have been eventful to say the least. In 2011, City were well beaten by Bayern in a 2-0 defeat, but the big talking point of that particular evening was the refusal of then-City striker Carlos Tevez to come on as a substitute following a row with manager Roberto Mancini.
Then a year ago, Bayern led 2-0 against City before Manuel Pellegrini's side staged a stunning fightback to win the game 3-2 at the Allianz Arena.
Tonight, the two sides renew pleasantries in the first game of Group E, with Roma taking on CSKA Moscow in the other fixture of the group.
German newspaper Bild are fairly well connected when it comes to Bayern, and they've set about trying to predict Pep Guardiola's line-up for the game - and there are two huge absentees.
Wingers Arjen Robben and Franck Ribery have been a devastating duo for Bayern in recent years, but after injury concerns, it appears that both will be left out of the starting line-up but could take their places on the bench in case Bayern need a late push.
Holger Badstuber, Javi Martinez, Bastian Schweinsteiger and Thiago are also set to miss out, with Juan Bernat starting at left back and David Alaba pushing forward into holding holding midfield alongside Xabi Alonso. In terms of replacements for Robben and Ribery, Guardiola can call upon Thomas Muller and Xherdan Shaqiri, demonstrating Bayern's incredible depth, whilst Mario Gotze should play behind his former Borussia Dortmund team mate Roberto Lewandowski.
Despite the injury worries, Bayern's amazing squad means that their starting XI should still be a tough test for City as the two sides kick off their Champions League campaigns.