The former Magpies striker believes the club made the right choice selling Fraser Forster.
The Magpies boss will face his former side at St Mary's and will no doubt feel he has a point to prove to them - especially after they thrashed Newcastle 4-0 last year - and to his own fans, who have put him under a huge amount of pressure lately.
But another of those involved at the weekend will also be facing a former club, one that sold him back in 2012 after a series of loan spells away from St James' Park.
That man, Fraser Forster, is now England's no.2 goalkeeper and a Premier League regular at Southampton. And Newcastle fans could be forgiven for being wary of his desire to prove a point himself.
Former Magpies striker Peter Lovenkrands, however, says the club were right to sell the 26-year-old. Why? Because Tim Krul is the better stopper.
"They chose Tim Krul over him a few years back and Forster will want to show they made a mistake. He is England No 2 now but for me Tim Krul is still the better goalkeeper," Lovenkrands wrote in the Newcastle Evening Chronicle.
"For Forster now it is about showing Newcastle he is the better goalkeeper and it will be interesting to see that key battle on the day unfold as they go head to head.
"I think at the time it was a close decision for United. Krul probably got the nod on experience.
"At the time I think Newcastle made the right decision and Krul has done a fantastic job since. He is a very experienced goalkeeper now."
Pardew's side are yet to win a Premier League match so far this season, although the Saints have one gone one better, winning once and drawing once during their opening three games.