Rodgers believes Balotelli is in good condition and could be in line for his debut on Sunday lunchtime.
Balotelli completed his £16 million move to Liverpool from AC Milan on Monday, strengthening the Reds' striking options, and the manager suggested he could be fit enough to be involved against Spurs.
The Reds's boss told the Liverpool website: "I think by the weekend [he'll be ready to feature].
"He's been into pre-season and he's played three 45-minute games. He might not be up to full match speed, but he's looking fit.
"We've done some analysis on him. The medical and sports science team have worked with him already and he's in very, very good condition.
"He's in to work and he'll be available for the squad for the weekend."
It's unclear whether Rodgers feels the Italian forward will be able to play a full 90 minutes but it seems almost certain he will be part of the squad that travels to White Hart Lane.
Rodgers may opt to start with Daniel Sturridge up front alone like he has done in the opening two games of the Premier League campaign, but there is the option of starting Balotelli alongside Sturridge with Rickie Lambert possibly being used from the bench - like he has done against both Southampton and Manchester City.
The 24-year-old's inclusion in the squad will make team selection ahead of Sunday lunchtime's game intriguing.