They had the opportunity to be re-united this summer, and what a midfield pairing what would have been, but Arsene Wenger decided not to buy back the Spaniard, who signed for rivals Chelsea instead.
Perhaps worried Cesc could overshadow or stunt the development of Ramsey, from a neutral perspective it has allowed both stars to shine in their respective sides.
Last weekend Ramsey scored a crucial late winner as Arsenal beat Crystal Palace 2-1, and Cesc Fabregas created two goals on his debut as Chelsea triumphed 3-1 at Burnley.
The Arsenal man won more tackles than Cesc did, but did not create a single goalscoring opportunity. He did however make more successful passes in the final third, as Arsenal piled the pressure on Palace.
It will be interesting to see who comes out on top in the battle for dominance over the course of the season, this coming weekend Ramsey's Arsenal travel to Everton, while Cesc's Chelsea host Leicester City.
Quizzed on the pair of them this week, Arsene Wenger told ESPN: "What is good in life is that someone moves out and someone else takes over and he has developed.
"Ramsey has a different style to Fabregas, but he has developed into a player with huge potential. There is more coming out of Ramsey. He is younger than Cesc and the potential is there to get more out of him."