Former left-back Olivier Bernard believes Sissoko will be the next big name to leave St James' Park if there is no sign of investment in the first team.
Speaking to The Chronicle, Bernard said that although Debuchy's exit was imminent, the club still have a real chance of holding on to the likes of Moussa Sissoko if there is enough investment dedicated to rebuilding the squad.
Bernard said; “It is not about him (Debuchy). It is the alarm bells his departure sets off amongst the likes of Moussa Sissoko – I don’t think he desperately wants to leave.
"However, if he sees more team-mates sold off and gets a good offer elsewhere, then I can see him going."
Bernard spent five years at St James' Park between 2000 and 2005, and was part of Sir Bobby Robson's team that reached the knock-out stages of the Champions League.
The Frenchman returned briefly in 2006 to finish his career with the Magpies, and is still a prominent figure in North East football after buying non-league Durham City in 2013
The 34-year-old is not the first former Newcastle player to speak out regarding their concerns for the club.
Andy Cole openly criticised owner Mike Ashley last month and echoed Bernard's views that serious investment was needed, stating also that the fans 'deserved a lot better than what they are getting'.
Sissoko has been at Newcastle for little over a year after signing in January 2013, but the Frenchman is already set to hold talks with the Tyneside club this week with his immediate future seemingly undecided.
The Magpies have struggled to rediscover the form that originally attracted Sissoko to the club.
After an impressive campaign finishing fifth in the Premier League in 2012, Newcastle spent last season languishing in the bottom half of the table and with those short-lived glory days well and truly in the past, Alan Pardew now has a real task ahead rebuilding his squad.
On the positive side Newcastle have completed the signing of Siem De Jong from Ajax, and this is seen to be a step in the right direction. But with a replacement still required for Yohan Cabaye and with Matthieu Debuchy close to a deal with Arsenal, more activity is needed otherwise the club may have a further exodus on their hands.