The Zenit Saint Petersburg man said that he was hopeful of being fit for Tuesday's World Cup Group A after pulling out of training with a leg muscle problem.
The injury occurred on Sunday, just two days before the game, but the 27-year-old still hopes to be fit in time.
"I felt a slight pain in my thigh that was uncomfortable during our training. I decided to stop playing as a precautionary measure," he said.
"There are only two days left before the next match but I'm fine and at ease, and I hope to be 100 per cent and get on to the pitch."
Despite his upbeat outlook when speaking to the media, Hulk looked highly distressed when he pulled up with the injury. He sat on the bench while his teammates remained on the pitch and was consoled by training staff as it looked like his World Cup dream could be in doubt.
Hulk is particularly focused on playing against Mexico as the match takes place at Fortaleza in the north-east of the country, not far from Campina Grande where the striker was born.
"Because I'm from the north-east, my whole family's going to be there so of course it's not a match I want to miss," he said.
"For the World Cup we want to play in every game, especially when we're playing at home - it's something special."
The match against Mexico will almost certainly decide who tops Group A. Brazil ran out 3-1 winners against Croatia in their first game, while Mexico beat Cameroon 1-0 to set up Tuesday's showdown.
The winners of Group A will avoid facing the team that finishes top of Group B - which features the Netherlands and Spain - in the first knockout round.