In their only previous meeting, Mexico came out 1-0 winners in a friendly more than 20 years ago on September 22, 1993.
The only goal was scored by the Mexican striker Daniel Guzman and Mexico will hope to make it two wins from two when they meet Group A rivals Cameroon this evening.
However, el Tricolor have never beaten an African side at a World Cup in three previous attempts, losing once and drawing twice.
Legendary striker Roger Millar would have played in the meeting in 1993, and Cameroon will rely on their current talismanic striker Samuel Eto'o to lead the attack for the Indomitable Lions this time around.
The 33-year-old has been directly involved in their last four World Cup goals, scoring three and getting one assist.
Mexican defender Juan Hernandez played in the game 21 years ago, but the focus will be on a different Hernandez tonight as Manchester United striker Javier Hernandez looks set to start on the bench.
'Chicharito' will have to make an impact as a substitute as it appears as though coach Miguel Herrera has opted for former Tottenham man Giovanni Dos Santos to play alongside Oribe Peralta.
Peralta has scored eight goals in his last six competitive matches for Mexico and will need to spearhead the attack again in their World Cup opener.
A low scoring affair could be on the cards again as neither side can afford to lose the opener, and Cameroon will want to win what would be just their second win in 14 matches at World Cup finals.