The news could spell bad news for Roberto Soldado, who has flopped since his £26 million move from Valencia last summer.
The new Spurs boss is planning to use the Togo striker as his main spearhead in the 4-2-3-1 formation he favoured at Southampton, meaning the Spanish forward could be set for a backup role despite breaking the club's transfer record upon his arrival, last summer.
According to the London Evening Standard, Adebayor, whose White Hart Lane career was revived under Tim Sherwood last year, will take precedence up top as the Pochettino begins to formulate his plans for next season.
The former Saints boss likes to use strong forwards in his preferred formation, and there is a feeling that Soldado would not be up to the task.
The Spaniard endured a miserable debut campaign in the Premier League, scoring just six times in 28 appearances, with four of those coming from the penalty spot.
Meanwhile Adebayor netted 11 times in 21 appearances after Sherwood brought him in from the cold upon his arrival last December.
It remains to be seen if Soldado is content to be second choice at White Hart Lane, and the former Los Che star has been linked with a switch back to his homeland, with Atletico Madrid reportedly showing an interest.
However the Los Rojiblancos' fans started an online campaign against signing the 29-year-old, and Spurs may have to take a hit if they are looking to offload the striker.
Soldado will turn 30 at the end of next season, and the North Londoners are unlikely to recoup the huge outlay they paid Valencia for him last August.