The £40 million rated Borussia Dortmund star is now staring at the distinct possibility of missing the World Cup in Brazil, which creates a number of knock on effects.
Every report has suggested that the Spaniard has been told he can leave the Nou Camp this summer but in light of Reus’ injury, Barca may take the option of proceeding with caution and waiting until after the World Cup to do a deal.
The Catalan press claimed earlier this week that Barca had a verbal agreement in place to sign Reus, after speaking to his representatives while concluding another deal last season.
Reus was visibly in agony after he suffered the injury to his left ankle and had to be carried off the pitch by German physios before going to hospital to have the problem assessed.
The results of the tests carried out but if Reus hasn’t, and it’s a big if, suffered bad ligament damage then he stands an outside chance of featuring later in the group stage ahead of the second round.
Luis Enrique, Barcelona manager, may be reluctant to commission a return to the Premier League for Fabregas while the fitness of the man reportedly lined up to replace him is unclear.
The news could also mean greater exposure for Arsenal star Mesut Ozil in Brazil, after he looked set to start behind Reus as Germany prepare for group games against Portugal, Ghana and the United States.
Ozil excelled when he came on against the Armenians after being heavily criticised by the German press last week for his performance in the draw against Cameroon.
Fortunately for the German, they have plenty of cover in central midfield but it will be a shame if Reus’ injury prevents fans from watching him at the World Cup and a bigger shame if it puts the brakes on Fabregas’ Premier League return.