The Netherlands international has confirmed that he will be fine for the World Cup and he came off against Wales as a precaution.
With countryman Louis van Gaal taking over at Old Trafford ahead of next season, the Red Devils fans will hope the former arsenal hitman will be fighting fit for the start of the domestic campaign.
Many will have had their hearts in their mouths as Van Persie came off during a pre-World Cup friendly against Wales last night, with another potential injury on the cards.
However, the attacker has confirmed that there is no need to worry and that his substitution was a mere precaution.
"You do not have to worry," Van Persie told Voetbal Primeur.
"I had a little pain in my groin. My change was just a precaution.
"I would not really even call it an injury. Next week is the most important thing."
Van Persie is expected to lead the line for Holland in Group B at the World Cup and will face Spain, Chile and Australia.
The forward is a favourite of Van Gaal, which could bode well for United next season.