With Pochettino swapping St Mary’s for White Hart Lane, who should succeed him? Former Swansea, Manchester United and England bosses feature.
"We have begun the search for a new high-calibre manager," he said. "We will be looking for a manager that shares our values, our principles and our philosophy; a manager who can continue to grow the first team and build on our strong foundation.”
Here are five early favourites for the role.
Murat Yakin – 4/1
Yakin is a 39-year-old, ex-Switzerland international defender, formerly in charge of Chelsea-slaying FC Basel.
The two-time Swiss Super League champion with Basel is unemployed, with Southampton’s Swiss owners reportedly keen on their compatriot. His reported lack of English might be problematic, though it’s a situation familiar to the club. With a managerial win percentage of 50%, Yakin far surpasses his potential predecessor Pochettino’s 35%.
Ronald Koeman – 9/2
Linked with Swansea in March, Feyenoord boss Koeman has cited an ardent interest in Premier League management. The 51-year-old European Cup winner has managed seven clubs across three countries with a 55% win percentage, victorious in Spain’s Copa Del Rey with Valencia, the Portuguese Supercup with Benfica and the Dutch top flight on three occasions: twice with Ajax and once with PSV. Koeman is perhaps the most successful managerial candidate on the list.
Michael Laudrup – 7/1
The stylish ex-superstar-turned-manager has been without employment since leaving Swansea City and would no doubt seize the opportunity to manage Southampton.
His desire to play expansive, possession based football would suit Southampton’s players, and the chance to work under such a celebrated ex-pro would excite. The Dane led Swansea’s 2013 League Cup victory and he has a managerial win percentage of 45% - although this dipped to 35% while in Wales.
Steve McClaren – 10/1
The ex-England manager currently leads Championship play-off finalists Derby County. At 53, McClaren is the oldest of the bunch with a coaching CV spanning nine clubs over almost two decades.
A win percentage of 45% over 500+ games is impressive, and along with his reputation for pushing young, English talent, he could be perfectly suited to the Saints' role. However, although linked, McClaren is reportedly committed to Derby’s promotion push next season.
David Moyes – 14/1
The former Everton boss is unemployed after his widely publicised chop from Manchester United. Perhaps not suited to his last club, the 51-year-old Scot’s Everton experience suggests Southampton might be a surer fit.
A developer of young talent and used to squeezing the best out of his players, a spell at the Saints could revitalise his career. Again, a win ratio of 45% is equal to most other candidates, but his Premier League experience could prove invaluable.