Southampton: Boruc, Clyne, Fonte, Lovren, Shaw, Wanyama, Cork, Schneiderlin, Davis, Lallana, Lambert
Subs: Gazzaniga, Ward-Prowse, Guly, Chambers, Hooiveld, Reed, Gallagher
Manchester United: De Gea, Smalling, Ferdinand, Vidic, Evra, Januzaj, Fletcher, Kagawa, Welbeck, Mata; van Persie
Subs: Amos, Carrick, Cleverley, Lawrence, Young, Valencia, Hernandez
This is a very important game for Mauricio Pochettino and possibly his last in charge of the Saints according to reports.
Tottenham are apparently very keen on signing the Saints boss as their manager for next season, but Pochettino will be focused on condemning Manchester United to another defeat.
Southampton will also have some very good players on display who have been linked with summer exits.
For some United fans, this is the match they have been waiting for because it signals the end to what has been a terrible season.
Several players in United’s squad could be playing their last game, with potential new boss Louis van Gaal tipped to make plenty of changes over the summer.
Giggs showed faith to some youngsters in the win against Hull City but will want to give more experienced players a chance, especially with the start of the World Cup looming in a few weeks.