Liverpool and Manchester City should both win - while Arsenal, Everton and Chelsea are also backed to win away from home.
Cardiff v Chelsea: 1-3
Cardiff are down and Chelsea re third this game essentially counts for nothing but pride. Class usually shines through in these games and Chelsea have more of that so a comfortable win looks on the cards.
Fulham v Crystal Palace: 1-1
A London derby between a team that are down and one who have pulled off a miracle to stay up. A tight game which should end in a draw.
Hull v Everton: 0-3
Hull have one eye on the FA Cup Final and Everton have one eye on next season. It should be a rather calm affair, but Everton should be confident of a comfortable win.
Liverpool v Newcastle: 6-0
Seriously, this is my prediction. Newcastle cannot wait for the season to end and Liverpool want that title.
I think they will rip into Alan Pardew’s dysfunctional outfit in hope of City slipping up at home against West Ham.
Manchester City v West Ham: 3-1
Expect a little drama, but that is it, as City should cruise to a title win with a win against Sam Allardyce’s men - in what might be his last game in charge.
Norwich v Arsenal: 1-2
Another game with little significance which should see the better team come through unscathed. Norwich can start planning for life in the Championship.
Southampton v Manchester United: 1-1
Should be an interesting game, and might be the last ever one for Pochettino, Lallana and Shaw for The Saints.
Meanwhile Giggs will want to go out with a bang - but a draw seems a sensible guess.
Sunderland v Swansea: 2-2
Another game between two teams just happy to still be in the Premier League next season - in which a draw will be a welcome, entertaining, result.
Tottenham v Aston Villa: 3-1
Tim Sherwood’s last game in charge? Perhaps. Expect him to go out with a bang.
West Brom v Stoke: 0-1
Another dead rubber, and don’t expect too much from this game. Stoke should have the edge in a tight contest.