Manchester United: De Gea, Jones, Ferdinand, Vidic, Evra, Nani, Carrick, Fletcher, Young, Mata, Hernandez
Subs: Amos, Smalling, Valencia, Fellaini, Januzaj, Welbeck, Van Persie
Sunderland: Mannone, Vergini, Alonso, Cattermole, O'Shea, Brown, Larsson, Colback, Wickham, Johnson, Borini
Subs: Bardsley, Altidore, Ba, Giaccherini, Bridcutt, Scocco, Ustari
Ryan Giggs will be hoping his Manchester United side can build on their dominant display against Norwich City last weekend.
It won’t be easy for United as Sunderland are fighting to pull further clear of the bottom three and they will take great confidence from the fact they knocked United out of the League Cup earlier this season.
A win for United will put them within touching distance of Tottenham Hotspur, currently losing at West Ham United, as they fight for some form of European football next season.
Sunderland are currently level on points with Norwich City and a victory for them would move them to 35 points, level with Aston Villa who host Hull City at Villa Park.
Gus Poyet will urge his side to believe they can win against the odds as United continue their hunt for a new permanent manager.