Both players enjoyed good days at the office, although in Reus's case, it still wasn't enough to see him progress to the Champions League semi-final.
The German attacker, did however, scare the La Liga outfit with a superb brace, and in truth, it could have been even more. Reus proved pivotal in the fightback against Real Madrid, with his constant energy and threat in and around the box.
Along with his two goals, he created a staggering five goalscoring opportunities for his teammates, which unfortunately for the German, none of them could capitalise on.
Similarly, Toni Kroos was pivotal in Bayern's win over Manchester United, although he did play a quieter role than Reus.
The central-midfielder filled the 'Schweinsteiger' role perfectly, which was highlighted before the match as a possible problem area for the home side.
The 24-year-old was huge in influencing the play for the home side, and in truth, was arguably the most important player in Bayern's dominant possession game.
He had 94 touches of the ball, making 83 passes with an 86% success rate, as well as creating three goalscoring opportunities. And when compared with United's equivalent, Michael Carrick, the differences are quite staggering.
Carrick made half the touches with nearly a third of the amount of passes, along with a much worst pass success rate.
A poor performance from the England international who was tasked to give Man United the impetus in the game against Bayern. A role that few footballers in the world will envy.
However, the question now is, can Manchester United still sign the duo even without Champions League football, and potentially no European football whatsoever? Many would predict not.
Although, reports suggest Manchester United must still fancy themselves in the race for Kroos, as Ed Woodward is supposedly trying to thrash out a deal for the talented 24-year-old as soon as tomorrow morning.
David Moyes said after the game that his transfer targets are 'keen to come', and they accepted a lack of Champions League football would be a 'short-term' setback.
Whether that will be the case on both fronts remains to be seen.