Despite the former's eight-year headstart on the Arsenal goalkeeper, both have already led distinguished careers in English football and played their part in this season's Premier League campaign.
Cech, 31, came to Chelsea in 2004 and has since won three Premier League titles, four FA Cup trophies and two League Cups - as well as both the Champions League and the Europa League.
Szczesny, the younger of the two at 23, joined the Gunners in 2009 and, by contrast, is yet to win a major trophy at the club.
That could well change this year, however, with Arsenal favourites to lift the FA Cup and just four points off Chelsea in the league. A win against the Blues tomorrow - in Arsene Wenger's 1,000th game in charge of the north London club - would put Gunners fans in dreamland.
Jose Mourinho, though, has never lost a league match at Stamford Bridge - and Cech has often played a crucial role in keeping that record intact.
The question is: who has the better statistics in the Premier League this season?
|Name||Saves||Diving Save||Good High Claim||Punches||Accurate Goal Kicks||Clean Sheet||Apps|
As Opta stats show, Chelsea fans may want to look away now. Despite playing one less game than his west London counterpart, Szczesny trumps the Czech goalkeeper in almost every key area.
The only department in which the 23-year-old does not surpass the Blues' no.1 is clean sheets but, even then, both shot stoppers have the same number.
Szczesny has made both more saves and diving saves than Cech this term, while he has also made 10 more punches and 13 more good high claims from crosses. Even the Poland 'keeper's goal kicks are statistically superior, having made 30 more accurate passes from a goal kick.
But one important factoid does act in Cech's favour - and it is possibly the most important of all. Indeed, the 31-year-old has conceded less goals than Szczesny, despite playing a game more.
Having let in 23 goals this season, Cech has conceded five less than the Arsenal goalkeeper, which could be viewed as the five the Polish stopper let in against Liverpool at Anfield.
Who, though, will concede the least goals tomorrow?