All the latest injury news ahead of Manchester United's key Champions League match:
Jonny Evans: The Manchester United centre-back missed training yesterday with a calf injury which has kept him out for more than a month and is unlikely to start the match.
Chris Smalling: Smalling also missed training, recovering from a hamstring injury although has not been officially ruled out.
Nani: Winger returned to training last week for the Red Devils, but did not make the bench against Liverpool. He will be keen to return to action with a bang.
Javier Hernandez: The status of the Mexican remains unclear. He was not pictured in training yesterday although Moyes said last week he was in contention for the Liverpool game. He has not appeared since early February and has been nursing a knee problem.
Big decisions for David Moyes:
They say don't change a winning side, and David Moyes usually does - so a mix-up from the weekend's losing one is a certainty to some degree.
The problem is the side selected against Liverpool was close to being United's strongest available side on paper, so Moyes must decide who to sacrifice.
The big decision is likely to come at the back, Moyes must choose whether to go with the experience of Rio Ferdinand alongside Nemanja Vidic, or Phil Jones who featured against Liverpool.
In midfield it is likely to be two from Michael Carrick, Tom Cleverley or Marouane Fellaini. The Belgian missed the first leg through injury, and Moyes may be tempted to hand him a chance rather than Cleverley, who was rested at the weekend.
If Moyes wants to go all out and attack, changing up a front four of Rooney, Januzaj, Van Persie and Mata is essential, with the former Chelsea man cup tied.
He didn't even make the bench in the first leg, although we expect Januzaj to start here. Moyes' comments yesterday regarding Shinji Kagawa 'having a role to play' potentially indicate a surprise start for the well-rested Japanese international, and it is the perfect stage for him to show his worth.
Predicted XI: De Gea, Rafael, Ferdinand, Vidic, Evra, Carrick, Fellaini, Kagawa, Januzaj, Rooney, Van Persie.