Manuel Pellegrini's side were made to pay for losing the first leg 2-0, as they simply couldn't break down Barca's defence in the second leg to get themselves back into the tie. Vincent Kompany's consolation arrived late in the game, meaning City are out at the first knockout stage.
Pellegrini chose to go with a five-man midfield consisting of Samir Nasri, Yaya Toure, James Milner, Fernandinho and David Silva, leaving Sergio Aguero to lead the line on his own despite only just recovering from injury.
But Aguero's lack of match fitness showed with a terrible showing the first half, touching the ball just six times before he was hauled off for Edin Dzeko at half time - and City looked better for the Bosnian's introduction, as he offered a physical presence up front that Barcelona struggled to deal with.
City fans were obviously disappointed at the Argentine's contribution - or lack thereof - and here are some of the tweets about the former Atletico Madrid striker from the first half of the game.
Serious question, has Aguero touched the ball yet? #MCFC— andrew knowles (@andrewknowles10) March 12, 2014
Aguero quiet so far, #MCFC need to get him involved. Barca defence leaving space to exploit down the channels.— Køjø Øwusu-Økyërë (@KojoOkeleji) March 12, 2014
#mcfc need Aguero to grab the game by the balls. City can't afford for the game to pass him by.— Santino (@SonnysView) March 12, 2014
I would expect a litle more from aguero..Also, milner looks too shabby, slipping all the time..Let's get navas and negredo on now..#mcfc— Kun Arjun (@Don___Corleone_) March 12, 2014
Brilliant from Vinny and Ferna. Nasri and Aguero ineffective but the much maligned Dzeko put a shift in. All about the League, do it. #mcfc— Kenny Court (@kennyjnr1) March 12, 2014
If only Silva or Nasri had taken those chances. Biggest probs we have is Aguero is invisible, & all the players on yellow cards #mcfc— Lee Bromfield (@LeeBrom) March 12, 2014
Aguero been quiet, do we stick with 5 in midfield or put another striker on? #Mcfc— Paul Moore (@Mad1moorsey) March 12, 2014