The incredible statistic has spanned over 38 games.
Last night's 0-0 draw with Arsenal had its positives for David Moyes.
For one thing, Manchester United did not lose at the Emirates Stadium, meaning they are unbeaten against the Gunners this season.
But, in failing to win another game on the road, Man United also ensured an unwanted personal landmark for their manager.
Indeed, Moyes has now gone 38 games - and 12 years - without ever winning at Arsenal, Chelsea or Liverpool. And let's not forget that the 50-year-old never managed to beat United themselves during his time at Goodison Park, either.
In 49 Premier League away games against the 'Big Four', Moyes' record reads: W0 D19 L30.
Most of those games, of course, came during the Scot's time at Everton - yet Moyes has now had three cracks at the whip as United boss, failing to win on each occasion.
Sure, he didn't lose... But Arsenal were there for the taking, providing Moyes with one of his best chances ever to finally break his duck.
United were unable to make the vital breakthrough, however, while both sides flattered to deceive in a game neutrals will be quick to forget.
The Scot will now have to wait until next season to try and win at the Emirates, Anfield or Stamford Bridge in the league - and he'll be hoping 12 years doesn't become 13.
Could Moyes go his whole career without winning at Arsenal, Chelsea or Liverpool?