To be played on Tuesday 28th January 2014 at 20:00. Venue: Anfield, Liverpool.
Odds: Liverpool 11/13, Draw 3/1, Everton 7/2
Last season: 0-0
Preview & injury news
This is possibly the biggest Merseyside derby in the league since both sides were fighting it out for the title in the late 1980s, and they both have a real chance of claiming the fourth Champions League spot this season. Both sides are looking to bounce back from disappointing results against West Midlands opposition last time out in the league and return to winning ways with Tottenham firmly in the mix for the the Champions League spot and Manchester United lurking behind. If Everton were to prevail in this encounter at Anfield, it would be their first victory there since 1999 - when Kevin Campbell got the winner for the Blues.
Liverpool came back from two goals down to salvage a point in their last league match, at home to Aston Villa before professionally dispatching of Bournemouth in the fourth round of the FA Cup - whilst Everton missed the opportunity to go above Liverpool going into this game by letting their lead slip to West Bromwich Albion - but they comfortably booked their place in the next round of the FA Cup with a 4-0 victory at Stevenage.
On the injury front, Liverpool have a fairly lengthy list as they look to select the back four that has proved to be frail over the past few weeks. There are still question marks over the fitness of centre half of Mamadou Sakho who is still struggling with a hamstring problem, whilst Daniel Agger still has a calf problem and isn't expected to return until next month. Glen Johnson is out for an indefinite period of time, though there are murmurs he could return to action in late February. Joe Allen is an injury doubt after missing the cup tie against Bournemouth, whilst Lucas Leiva is no expected to return until March at the latest.
Everton also have their share injury problems with Bryan Oviedo the latest player to enter the Toffees' treatment following his horror leg break in the cup tie against Stevenage at the weekend. Ross Barkley is still being treated for an ankle injury, whilst it's too early for Seamus Coleman to return from a hamstring problem. Steven Pienaar and Gerard Deulofeu could both return from groin and hamstring problems respectively - whilst Arouna Kone and Darron Gibson are still recovering from long-term injuries. Sylvain Distin is rated 'touch and go' for the game.
Here are Liverpool's top league scorers this season
Everton's top scorers in the league this season
Here are their average possession stats:
5 players to watch
Simon Mignolet - The Reds' stopper has been going through a difficult period form wise and will be keen to put that behind him this week. He put in a terrific performance in the reverse fixture earlier on in the season and will be keen to rediscover that kind of form.
Leighton Baines - Baines will be relishing the task in this derby as he will have a Liverpool right-back up against him who hasn't played there regularly this season, and will look to cause the home side some problems. His final ball into the Reds' area could cause their centre-backs problems as well.
Jon Flanagan - The young full-back returned to action in the FA Cup at the weekend from a hamstring problem and played the latter stages at right back. However, he did impress in several games before his injury on the opposite flank so it will be interesting to see where the 21-year-old will line up.
Romelu Lukaku - Lukaku has bullied Liverpool on more than one occasion, both with West Brom last season, and this season he got two goals against the Reds. He'll be licking his lips at the prospect of continuing his good form against Liverpool, and is probably a good bet to get into double figures in the league in this fixture.
Luis Suarez - 22 goals this season and the only home game which he featured in and didn't score this season was the last one against Aston Villa. Suarez has developed a bit of a habit of scoring against Everton so will he strike again on Tuesday evening?
Earlier on in the season
Everton 3-3 Liverpool, November 2013
It was one of the most pulsating Merseyside derbies in over 20 years as the neutrals will have wanted both sides just to keep on playing. Philippe Coutinho stabbed home early on after Everton failed to deal with a Steven Gerrard corner. The Blues hit back almost immediately when Kevin Mirallas equalised after Martin Skrtel couldn't clear Leighton Baines' free kick. Liverpool retook the lead just before the midway point in the first half after a wonderful free kick left Tim Howard with no chance. Joe Allen missed a sitter which could have put daylight between the two sides before Romelu Lukaku scored from ten yards after his deflected free-kick was saved by Simon Mignolet. Everton lead for the first time after Lukaku got his second heading in a corner from Mirallas eight minutes from time. But substitute Daniel Sturridge headed home from Gerrard's free kick a minute from time to finish the scoring.