It will require a massive performance from Napoli if they are to qualify for the next round of the Champions League and even victory over the Gunners won't guarantee progress.
While tensions are expected to run high at the Stadio San Paolo tomorrow evening, Benitez has never disguised his admiration for opposite number Wenger.
"Wenger is the best tactician in the Premier League and he knows what his team need to do," the Spaniard said at his press conference.
"We need to play our game and focus on that not on what Arsenal are going to do.
"Arsenal can play a possession game or on the counterattack. We need to attack but with the right balance."
Pundits in Italy have been saying that Napoli's season could fall to pieces if they fail to get through as recent Serie A results have seen them fall off the Scudetto pace.
"We have nothing to lose. We have had a very positive competition and I came here for that.
"We were very unlucky to get such a tough group but for me it's always better to be a part of these games than to watch them on TV.
"Our game plan is to go for it. If they score one, we will try for four. We know Arsenal are very strong but we will give it a go."
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