Mesut Ozil and Sami Khedira are two players whose fate has been intertwined until this summer, when one left Real Madrid for Arsenal, and the other stayed to fight for his place - rejecting Premier League advances.
Last week both suffered with poor health, at dramatically differing ends of the scale. Mesut Ozil had flu, while Khedira tore a cruciate knee ligament in the friendly with Italy.
Both players missed the friendly against England, with Khedira now facing a race against time to even make the World Cup squad.
The news came as a real blow to Germany, with pundits considering the midfielder almost irreplaceable.
A writer for German newspaper Frankfurter Allgemaine, Christian Kamp even suggests an injured Mesut Ozil would be easier to deal with:
"The loss of Reus, Götze or possibly even a Ozil would be bad, but still nothing as fundamentally shocking. In the case Khedira but it's different. Of this variety Loew has players - and here you have to say well: we had just the one."
To correct Kamp however, Germany certainly did not struggle against England in midweek without Khedira, but perhaps that said more about the hosts.
The assertion does raise the question of whether Mesut Ozil is replaceable for Germany - and it's possible to see why many would believe so.
With attacking midfielders like Julian Draxler, Andre Schurrle, Toni Kroos, Marco Reus, Sidney Sam, and Mario Gotze all competing for places, they certainly are not short on options.
But here's the kicker, Mesut Ozil is the best of the lot of them, the player who has been there and done it on the big stage - standing out with Germany at World Cup 2010.
If we were Jogi Low picking a team to compete next summer, despite Khedira having his own unique style in the middle of the park, we would rather be picking Ozil.
image: © Ronnie MAcdonald