Despite Roma's miraculous start, Juventus v Napoli has been dubbed an early title decider by some pundits in Italy and will see Argentina's Carlos Tevez square off against Argentina's Gonzalo Higuain.
Roma will expect to bounce back from their first dropped points by beating Sassuolo, while Chievo v AC Milan may well lead to a managerial casualty as neither Massimiliano Allegri nor Giuseppe Sannino can afford a defeat.
WEEK 12 IN NUMBERS:
10 - Ten Juventus players have scored so far this season, compared to eight from Napoli's squad. JUVENTUS v NAPOLI
46 - The number of games Inter boss Walter Mazzarri spent in charge of Livorno. It was the 2003-04 season and his 20 wins, 19 draws and seven defeats were enough to win promotion from Serie B. INTER v LIVORNO
25 - Genoa have hosted Hellas Verona 25 times between Serie A and B. The visitors have only won twice. GENOA v VERONA
6 - The referee for Atalanta-Bologna has been in charge of six games this season - the home side have won twice, three were draws and the away side triumphed once. ATALANTA v BOLOGNA
3 - Cagliari have lost three games on the bounce. Since beating Catania the Sardinians have lost to Lazio, Bologna and Verona. CAGLIARI v TORINO
7 - Chievo have only scored seven times this season. They are equal with Catania for the unenviable statistic of worst attack in Serie A. CHIEVO v AC MILAN
0 - Lazio haven't won away yet this term - they have drawn two and lost three, hence the pressure on boss Vladimir Petkovic. PARMA v LAZIO
22 - The gap in points between Roma and Sassuolo. ROMA v SASSUOLO
4 - The number of penalties scored by Fiorentina this season, the most in Serie A. FIORENTINA v SAMPDORIA
7 - The number of home wins Catania have secured in the last 14 against Udinese - the visitors won three and four were draws. CATANIA v UDINESE
This round-up appeared originally in Italian on Tuttomercatoweb.com.
The Sack Race:
It's a tense period in Serie A and at least four coaches could face the axe if they don't get the result they need. Massimiliano Allegri and Giuseppe Sannino go head to head in Verona as Chievo meet AC Milan. There is still a lot of pressure on Lazio boss Vladimir Petkovic who many feel is on the way out is he can't beat Parma and Sampdoria's Delio Rossi faces a daunting trip to Fiorentina needing an unlikely win.
Our top tip:
Roma should return to winning ways against Sassuolo and could run up a healthy score against Serie A's weakest defence. Worth backing the Giallorossi with a one or two-goal handicap to get some decent odds.