Wins for Arsenal, Manchester United, Liverpool, Southampton and Tottenham Hotspur - while Chelsea and Manchester City should share the spoils.
Here they are ....
Crystal Palace v Arsenal: 0-3
Palace are now managerless, and I struggle to see how anyone can do a better job at Selhurst park than Ian Holloway was already.
There are rumours of Arsenal resting players, but I doubt that, The Gunners should field a strong team and put The Eagles to the sword.
Aston Villa v Everton: 1-1
Everton and Villa have both looked like two teams who will flirt with the top-half this season, with Everton perhaps the stronger of the two.
But in the battle of the Belgian strikers, Benteke v Lukaku, chances are both will score in a close draw.
Liverpool v West Brom: 2-1
The Baggies have put in some pretty solid performances against the bigger teams this season, look at Manchester United and Arsenal.
But Liverpool have real hopes of a top-four finish this term and will not be complacent against Steve Clarke’s men.
Manchester United v Stoke: 2-0
Things are still a struggle for David Moyes, with the win against Real Sociedad a brief moment of respite.
But The Potters, after a good start, are looking like the confused outfit many predicted at the start of the season - and United should have no difficulty swatting them aside.
Norwich v Cardiff: 1-0
This could prove to be a big game come the end of the season, as both these teams are sure to be near the relegation zone.
But with the home crowd behind them The Canaries should have enough in their locker to win the game.
Southampton v Fulham: 3-1
I know that The Cottagers have a pretty impressive performance on Monday behind them - but United have an impressive season behind them.
At St Mary this should be a non-contest - but never say never, if Patijm Kasami and Steve Sidwell produce moments of magic again then who knows?
Sunderland v Newcastle: 2-2
Poyet admitted this week that he has inherited an unbalanced outfit from Paolo Di Canio, and this is not exactly the best time to have to play your local rivals.
But until they capitulated against Swansea they showed signs of being a slightly reformed team and that coupled with pride should be enough to avoid defeat against Newcastle United, but a win is beyond them.
Chelsea v Man City: 1-1
A big game at Stamford Bridge as two title rivals go head-to-head. Mourinho and Pellegrini’s tactics will decide the outcome of this match, but I consider both teams pretty even right now - so a score draw seems likely.
Swansea v West Ham: 1-0
West Ham’s no striker system showed its limitations against Manchester City last week, but that sort of system against the style Swansea adopt is again likely at The Liberty Stadium.
But I think Laudrup’s men will have enough to sneak the victory against their defensive opponents.
Tottenham v Hull: 2-1
I have read a lot about Spurs giving Hull a thrashing this weekend, but I doubt it.
They have struggled to that so far, instead winning by the odd goal or two - and that is likely to be the result for AVB and co this weekend.
What are your predictions ahead of the weekend fixtures?
image: © OliverN5