Juan Camilo Zuniga of Napoli has re-injured a serious knee problem from when he was a teenager.
It is becoming increasingly clear that Arsenal may have to find themselves a new right-back next summer, as Bacary Sagna looks set to become the latest player to move on due to the clubs rules on new contracts for over-30s.
As a general rule the club have only offered players of this ilk one year deals in the current era - which has seen many stars decide to move elsewhere for a long term commitment.
Sagna appears to be one such player, with the likes of Paris Saint-Germain, Monaco and Turkish rivals Fenerbahce and Galatasaray all set to make a move for the player in January - when he will have just six months left on his contract.
Losing Sagna may just feel like evolution for Arsenal fans, but the French international is having a decent season so far, and has demonstrated ability in the heart of defence so he will be missed.
But, with his expiration date fast approaching, plenty of potential replacements have been named in the press.
At the moment the likes of Roberto Rosales of FC Twente, Sebastian Corchia of Sochaux and Genoa’s young Croatian Sime Vrsaljko are all names being mentioned - along with the more hopeful chase of Manchester City’s crock defender Micah Richards.
Another name mentioned has been Juan Camilo Zuniga of Napoli.
The wing-back, who can play at both right and left back, has been linked with Arsenal in the summer and he is the archetypal Wenger full-back.
Attacking minded and technically sound, he is the perfect man to replace Sagna - accept he now appears to be one name that can be crossed off the list for now.
Zuniga was replaced by the recently returned from fitness Christian Maggio for the 2-0 defeat against Roma last night - after the Colombian spent time training alone this week with knee discomfort.
But what at first seemed a niggle now appears much more serious, with Zuniga set to undergo surgery on the affected joint this coming Monday.
Worryingly, it is the same knee he injured as a teenager with homeland side Atletico Nacional, which is grave cause for concern.
With that in mind - as well as a hefty price-tag and his ever approaching 30th birthday - his signing seems unlikely from Arsene Wenger.
image: © luigig