Arsenal had been linked with pursuing him all summer, with at one stage the player claimed to be on his way to the Gunners for a medical.
These claims proved premature, and it now seems that Napoli are to get their man to replace Edinson Cavani who they sold to PSG a week earlier.
For Arsenal it heightens the drama of their pursuit of Luis Suarez, but first there is the very real prospect that they could come face to face with Higuain on home turf in a fortnight.
On Saturday August 3, the Gunners face Napoli in their opening match at their very own Emirates Cup.
Surely the last thing the club want is to still be without a striker at that stage, and for the Argentine to be making his debut for the club and cause them a humiliating defeat on home turf.
The striker has already bagged one goal in England this pre-season, netting in a 6-0 win for Real Madrid against Bournemouth at the weekend.
Given the way the fates have conspired against the Gunners so far in the transfer market, via their own actions or bad luck, you wouldn't bet against him scoring a hat-trick.
Will Higuain make his point to Arsene Wenger?
image: © Jan S0L0