Liverpool will resist the temptation to give Luis Suárez too much rest, with Kenny Dalglish arguing that the euphoria from Uruguay's triumph in the Copa América and the striker's attitude should compensate for any lack of match fitness.
Suárez has scored or created every one of Liverpool's goals this season and his start contrasts with others who spent the southern winter competing for the Copa América. When Manchester City's trio of Argentinian players arrived back in England, their captain, Pablo Zabaleta, argued that they would all need plenty of rest throughout the campaign.
However, despite the fact that Suárez will be part of the Uruguay squad that travels to Kharkiv to play Ukraine on 2 September, Dalglish is confident the club will manage his form and fitness.
"I don't think he is jaded," said the Liverpool manager. "He had a break before they met up for the tournament and another break before he came back here. We would love him to play in every game, although that might not be practicable. But I have never come back from a tournament on a high like he has done, I was never that lucky.
"The adrenaline won't run out for Luis. He won't accept that success is finished for him. I am sure Uruguay will be conscious that they have got to manage their European players because it is a big burden on them to play all summer and then stage friendly matches as well.
"I suppose that after winning the Copa América they will want to keep their squad together and I am sure that, if the British countries won something, they would be milking it."
Suárez was said to have been influential in the arrival of the Uruguay centre-half Sebastián Coates, who underwent a medical on Friday after Liverpool agreed an £8m fee with Nacional. A deal to take Craig Bellamy back to Merseyside from Manchester City, who are willing to settle his contract, is also thought to be close.
Even though Suarez is 24, he is an increasingly influential figure at Melwood, although his manager would not speculate on whether he had it in him to be a future captain of Liverpool.
"We said right away when he came that he is a happy, smiley guy," said Dalglish. "He brought his little girl in and she is exactly the same, though she can't play, mind. He, Maxi Rodríguez and Raul Meireles are very close and he is happy with his life.
"The responsibility is not doing him any harm. He is very mature for his age. To go to Holland when he was 17 or 18 and speak fluent Dutch – which they say is one of the most difficult languages to learn — and become captain of Ajax was an achievement. It tells you a wee bit about him."
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