My Keepon was originally developed as a therapeutic tool for autistic children who can be overwhelmed by face-to-face interactions.
Last year, the creators teamed up with toy maker WOW! Stuff, which agreed to dedicate a portion of revenue to autism research.
Toys 'R' Us Inc. has exclusive rights to sell the robot in the U.S. and will begin lining the shelves with My Keepons in late October.
Bloomberg Businessweek's Ashlee Vance reports.